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19-20 Nov 2021

 

ANCHEM

 

ElsevierBV_EJP

 

Genos

 

PHC Biomedical

 

Polygen

 

Promega

 

Sygnis

 

Sygnis

 

Sartorius

 

Sygnis

 

Gliwickie Spotkania Naukowe 2019” - zadanie finansowane w ramach umowy nr 511/P-DUN/2019 ze środków Ministra Nauki i Szkolnictwa Wyższego przeznaczonych na działalność upowszechniającą naukę

Gliwice Scientific Meetings 2020

virtual conference

[GSM 2020 Conference materials]

 

Friday, 20th November 2020

9.00 – 9.15                 Opening of the conference and welcome addresses

9.15 – 11.30               Session I “Proteomics and Metabolomics

                                      (session co-organized by the Polish Proteomics Society)

                                      Chairman – Piotr Widłak

Piotr Widłak (NRIO, Gliwice): SEMPRA - Serum metabolome profiling in breast cancer risk assessment: introduction into the Polish-Norwegian project.

Guro Giskeødegård (NTNU, Trondheim): Serum metabolomics for risk assessment and treatment monitoring of breast cancer.

May-Britt Tessem (NTNU, Trondheim): Tissue multi-omics - why and how in Prostate Cancer.

Michał Mikuła (NRIO, Warszawa): Gut multi-omics profiling in Crohn’s disease.

Anna Wojakowska (IChB-PAN, Poznań): Metabolomic and proteomic approach for predicting response to neoadjuvant radiotherapy of colorectal cancer.

Dariusz Rakus (Wroclaw University): Quantitative proteomics to study brain aging and rejuvenation.

Piotr Suder (University of Science and Technology, Kraków): ZIKA NS2B-NS3 protease activity studied by iTRAQ labeling with nanoLC-MS/MS analysis.

Wojciech Cypryk (CMMS-PAN, Łódź): Proteomic and bioinformatic investigations of extracellular vesicles secreted during inflammatory response.

11.30 – 11.45             Break

11.45 – 14.45             Session II “RNA in Regulation Processes

                                     Chairman – Joanna Rzeszowska

Eric Miska (University of Cambridge): The short- and long-range RNA-RNA interactome of SARS-COV-2.

Fatima Gebauer (Centre for Genomic Regulation, Barcelona): Context-specific roles of the RNA binding protein UNR/CSDE1 in cancer.

Gunter Meister (University of Regensburg): Characterisation of RNA-modifying enzymes and their roles in cancer progression.

Markus Kretz (University of Regensburg): Mechanisms of long non-coding RNA-mediated control of tissue homeostasis.

Daniele Hasler (University of Regensburg): From miRNAs to RNA modifications: emerging functions of the La-related proteins (LARPs) in RNA biology.

Jan Medenbach (University of Regensburg): Cell stress-mediated regulation of translation induces chemoresistance.

Joanna Rzeszowska-Wolny (Silesian University of Technology, Gliwice):  Role of miRNA in translation of non-targeted transcripts.

14.45 – 15.00              Break

15.00 – 16.45              Session III “Bioinformatics and Mathematical Modeling

                                      Chairman – Marek Kimmel

Philipp Altrock (Moffitt Cancer Center, Tampa): Evolutionary dynamics of public goods games in cell populations

Marek Kimmel (Rice University, Houston): Modeling of bladder cancer evolution from field effects.

Joanna Polańska (Silesian University of Technology, Gliwice): Gene set enrichment for reproducible science.

Tomasz Lipniacki (IPPT-PAN, Warszawa): Innate immune response to viral infection at single-cell and population level.

16.45 – 17.00             Break

17.00 – 19.00             Session IV “Biotechnology in Medicine

                                     Chairman – Marek Łos

Dipanjan Chowdhury (Harvard Medical School, Boston): DNA damage response and cancer therapy.

Mohsen Akbari (University of Victoria, Vancouver): Localized delivery systems for management of glioblastoma.

Anna M. Czarnecka (NRIO, Warszawa): Why immunologist should become interested in sarcoma?

Katarzyna Szołtysek (Princess Maxima Center, Utrecht): Whole-genome CRISPR screen identifies mechanism of relapse in patient-derived paediatric ALL sample.

Anna Walaszczyk (Newcastle University): Therapeutic potential of senolytics in age related cardiovascular diseases.

 

19.00 - 19.30 Expert Session

 

Saturday, 21st November 2020

9.00 - 9.30 Expert Session

9.30 – 13.00               Virtual Poster Session

Short presentations of selected posters (4 minutes allocated to each presentation)

[I-1] Kamila Duś-Szachniewicz: A protein interaction map for cell-cell and cell-extracellular matrix adhesion in B-cell non-Hodgkin lymphomas.

[I-3] Łukasz Boguszewicz: The increased serum lipids and decreased N-acetyl-glycoproteins are positively correlated with a favorable response to induction chemotherapy in men treated for head and neck cancers.

[I-4] Marta Pałka: Lamin-associated proteome after heat shock induction – is lamin the novel element in stress granules aggregates?

[I-7] Agnieszka Skorupa: Sensitivity of 1H HR MAS NMR technique in detection of breast cancer cells in post-surgical specimens.

[II-1] Judyta Górka: RNase activity of the MCPIP1 protein inhibits tumor progression by regulating Wnt/β-catenin signaling pathways and epithelial- mesenchymal transition in clear cell renal cell carcinoma.

[II-2] Dorota Hudy: Pre-miRNAs features may influence the specificity of miRNA binding to AGO.

[II-3] Marta Podralska: Identification of irradiation-induced ATM-dependent lncRNAs.

[II-6] Markus Duechler: Small extracellular vesicles efficiently transport miRNA mimetics into monocytic cells.

[III-3] Anna Mrukwa: The impact of socio-economic state of society on COVID-19 development.

[III-4] Marcin Pacholczyk: In silico studies suggest T-cell cross-reactivity between SARS-CoV-2 and less dangerous coronaviruses.

[III-5] Kinga Lucińska: LCRAnnotationsDB: Database of annotations for low complexity regions in proteins.

[III-6] Patrycja Rosa: Comparison of transcriptomes of neurons, glia and non-specific neuroblasts in Drosophila melanogaster larvae

[III-8] Agata Wilk: Extended model of RNA interference.

[IV-1] Damian Kołat: WWOX may lose ability to regulate pro-tumoral AP-2γ but still possesses synergism with tumor suppressor AP-2α in high-grade bladder cancer.

[IV-5] Mariusz Hartman: Encorafenib alters melanoma cell proximity to the apoptotic threshold – implications for complementary therapeutic strategy using selective BH3 mimetics. 

[IV-8] Aleksandra Krystkowska: Cytotoxicity of styrylquinazoline derivatives and their application in glioblastoma therapy.

[IV-10] Dagmara Szeliga: Murine Breast Cancer: cell migration, tumor growth and metastases in mouse model with imaging using power doppler ultrasound and biochemical analysis.

 

11.00 - 11.30 Expert Session

 

[IV-13] Barbara Łasut-Szyszka: How can p53 inhibit the Wnt signaling pathway?

[IV-16] Małgorzata Adamiec: HSPA2 deficiency in keratinocytes may augment cytokine-induced psoriasis-like inflammation.

[IV-19] Patryk Janus: Heat Shock Factor 1 (HSF1) as a new tethering factor for ESR1 supporting its action in breast cancer.

[IV-22] Beata Biesaga: Lack of CD44 overexpression and application of concurrent chemoradiotherapy with cisplatin independently indicate excellent prognosis in patients with HPV-positive oropharyngeal cancer.

[IV-24] Justyna Czapla: Cancer-associated fibroblasts  in murine models of breast cancer (4T1) and colon carcinoma (CT26).

[IV-25] Daniel Fochtman: In ferroptosis-sensitive A549 cells, oxidative stress results in a specific lipid peroxidation death pathway.

[IV-26] Justyna Odrobińska: Micellar carriers and conjugates based on grafted or heterografted copolymers  - preliminary in vitro evaluation for cosmetic applications.

[IV-27] Maria Narożna: Novel oleanolic acid oximes conjugated with ibuprofen and ketoprofen downregulate the NRF2-ARE signaling pathway in human hepatocellular cancer cells in contrast to normal hepatocytes.

[IV-30] Anastazja Poczta: New melphalan analogs as compounds with improved antiproliferative properties.

[IV-36] Ewelina Pilny: Intramuscular administration of human adipose derived mesenchymal stromal cells accelerate muscle regeneration in a murine model of hindlimb ischemia.

[IV-37] Anna Sobiepanek: New melanoma prognostic markers and therapy monitoring by means of label-free methods.

[IV-39] Marta Cykowiak: Phytochemicals and their combinations affect the cell cycle, apoptosis and proliferation of HepG2 cells with different efficiency

[IV-40] Patrycja Przybyłowicz: Identification of genome wide discordant methylation patterns of the adjacent CpG sites.

[IV-44] Patryk Chudy: Detection of G-quadruplexes and heme oxygenase 1 interactions by proximity ligation assay.

[IV-47] Marcelina Musiałek: 3D imaging and characterization of the Rb-like protein activity changes in root meristem cells of Vicia faba subjected to replication stress.

[IV-54] Agata Hadryś: Effectiveness of Light-encoding oncolytic myxoma virus-loaded ADSCs to destroy murine pancreatic cancer cells.

[IV-62] Oliwia Kwapisz: Pathological changes of the liver caused by a high-fat diet.

13.00 – 13.15             Break

13.15 – 13.30             Presentation of awarded posters and closing remarks