Friday, November 22

9.00-9.10         Opening Address:
                Bogusław Maciejewski (Head of Center of Oncology, Gliwice)
                Joanna Rzeszowska-Wolny (Head of Dept. Exp. Clin. Radiobiology, Center of Oncology, Gliwice)
                Jan Kaźmierczak (vice-Mayor of Gliwice City)

9.10-11.30
Session I:        New trends in cancer therapy
Chairman: Mieczysław Chorąży

Beata Utracka-Hutka (Center of Oncology, Gliwice):
Chemotherapy - where are you going? Principles, new targets, challenges for the future.

Jan Walewski (Center of Oncology, Warsaw):
Therapy for lymphoma: current concepts and new approaches.

Jerzy Konopa (Technical University, Gdańsk):
Mechanisms of action as a basis for the development of new antitumor compounds.

Maciej Siewiński (Medical Academy, Wrocław):
Inhibitorotherapy of cancer.

Rafał Tarnawski (Center of Oncology, Gliwice):
How molecular biology may improve outcome of radiation oncology interactions.

11.30-11.50         Coffe break

11.50-13.30
Session II:        Transgenic organisms in agrobiotechnology and medicine
Chairman: Jan Szopa

Mieczysław Chorąży (Center of Oncology, Gliwice):
Genetically modified organisms - introduction.

Marcin Łukaszewicz (Wrocław University):
Transgenic plants overexpressing biologically active compounds.

Agnieszka Sirko (Institute of Biochemistry and Biophysics, PAS, Warsaw):
The potential of transgenic plants for subunit vaccine production.

Jerzy Jurka (Genetic Information Research Institute, Mountain View, USA):
Transposable elements: horizontal transfer and mechanisms of integration.

13.30-15.00         Lunch

15.00-18.30
Session III:        Genomics in medicine
Chairman: Barbara Jarząb

Helena Sztajer (Gesellschaft für Biotechnologische Forschung, Braunschweig):
Genomics and proteomics as a tools for analysis of phospholipid hydroperoxide glutathione peroxidase expression and transformation during spermatogenesis.

Włodzimierz Krzyżosiak (Institute of Bioorganic Chemistry, PAS, Poznań):
Translational regulation of the BRCA1 gene.

Marek Figlerowicz (Institute of Bioorganic Chemistry, PAS, Poznań):
Discovery of RNAi phenomenon - turning-point in functional genomics.

Catharina Larsson (Pharmacology Biovitrum, Stockholm):
Positional cloning of tumor suppressor genes in parathyroid tumorigenesis.

Patrick Gaudray (CNRS, Nice):
Deciphering Menin's interaction networks as a tool to tackle its biological role.

Barbara Jarząb (Center of Oncology, Gliwice):
Expression profiling by DNA microarray in endocrine - related cancer

20.00-24.00 Get together party.

Saturday, November 23

9.00-14.00
Session IV:        IV DNA repair, radiobiology and medicine
Chairman: Joanna Rzeszowska-Wolny

Marcel Blaese (University of Tübingen, Tübingen):
Role of cytoplasmic retinoic acid binding proteins CRABPI and II in regulating sensitivity of tumor cells to retinoids and ionizing radiation.

Kai Rothkamm (Universität des Saarlandes (Homburg/Saar):
Cell-cycle-dependent contribution of non-homologous end joining and homologous recombination to the repair of radiation-induced DNA double-strand breaks in mammalian cells.

Ingo Brammer (University of Hamburg, Hamburg):
Individual radiosensitivity: molecular mechanisms and clinical impact.

Elisabeth Ortmann (University of Vienna, Vienna):
Modulation of radiation induced apoptosis by antioxidant vitamins.

Antonina Cebulska-Wasilewska (Institute of Nuclear Physics, Kraków):
Predictive assays - comparison between various biological end-point and various doses.

Nadzeya Rabakon (Institute of Genetics and Cytology, Minsk):
Genetic efficiency of low-dose ionizing radiation in small mammals under chronic irradiation.

Barbara Tudek (Institute of Biochemistry and Biophysics, PAS, Warsaw):
Long-chain adducts of fatty acids derivatives to DNA bases, mutations and repair.

Krzysztof Szyfter (Institute of Human Genetics, PAN, Poznań):
Phenotypic and genotypic indications for an impaired DNA repair capacity in laryngeal cancer subjects.

Ryszard Oliński (Medical University, Bydgoszcz):
Oxidative DNA damage and repair; insight from determination of 8-oxoguanine and 8-oxo-2'-deoxoguanosine in extracellular fluids.

Grażyna Motykiewicz (Columbia University, New York):
DNA repair capacity in lymphoblasts from sisters discordant for breast cancer.

14.00-15.00         Lunch

15.00-15.30         Poster session

15.30-17.10
Session V:        Miscellanea
Chairman: Maria Wideł

Ludmila Drobot (Institute of Cell Biology, NAS, Lviv):
Ruk adaptor proteins - structural and functional features.

Wiesława Widłak (Center of Oncology, Gliwice):
Why spermatogenic cells are sensitive to elevated temperature. The role of heat shock proteins.

Dorota Rybaczek (Łódź University):
Premature mitosis (PCC) - a preserved ability of chromatin to replicate the DNA.

Olgierd Unold (Technical University, Wrocław):
Towards DNA based computer - the initial state.

Sergey Razin (Institute of Gene Biology, Moscow):
Chicken domain of alpha-globin genes: organization and regulation of globin genes expression.

17.10-17.30         Closing ceremony