Conference takes place in
Center of Oncology - M. Skłodowska-Curie Memorial Institute,
Branch in Gliwice,
Wybrzeże Armii Krajowej 15,
44-100 Gliwice

Friday, November 21st

9.00         Opening of the Conference
                Opening address: prof. Joanna Rzeszowska, President of the Organising Committee
                Welcome address: prof. Jan Kaźmierczak, Vice-President of Gliwice

9.15-11.00
Session I    Structure and Functions of the Genome
Chairperson: J. Rzeszowska

S.V. Razin (Institute of Gene Biology, RAS, Moscow)
Domain organization of human dystrophin gene

J. Filipski (Institut Jacques Monod, Universite Paris VII, Paris)
Mapping of the hot spots of recombination in human DNA cloned in S.cerevisiae

E. Youdinkova (Institute of Gene Biology, RAS, Moscow)
Organization of the chicken domain of alpha-globin genes

V. Philimonenko (Institute of Experimental Medicine, Prague)
Nuclear myosin I and actin are required for transcription of ribosomal genes

M. Malanga (Institute for Veterinary Pharmacology and Toxicology, Zurich)
Poly(ADP-ribose) reactivates stalled DNA topoisomerase I: relevance to genomic stability and cancer therapy

M. Gniazdowski (Medical Academy, Łódź)
Covalent binding of anthracycline antibiotics to DNA

11.00-11.30         Coffe break

11.30-14.00
Session II    Transgenic Organisms in Agrobiotechnology and Medicine - Centre of Excellence PAGEN Workshop on Modifications of Commercially Valuable Plants
Chairperson: J. Szopa

B. Müller-Röber (Potsdam University, Potsdam)
Transcription factor function search: combining genomics and single-gene approaches to discover new regulatory networks in plant biology

H. Hesse (Max-Planck-Institute, Golm)
Transgenic plants as a tool to improve sulfur amino acid content in plants

U. Schlüter (Risoe National Laboratory, Copenhagen)
Manipulation of flax for improved fibre extractability

M. Wróbel, Jan Szopa (Wrocław University, Wrocław)
Flax engineering for fibre improvement

M. Łukaszewicz (Wrocław University, Wrocław)
The antioxidant potential of transgenic plants

J. Hennig (Institute of Biochemistry and Biophysics, PAS, Warszawa)
Functional analysis of gluB gene in Solanum tuberosum plants

J. Zimny (IHAR, Radzików)
Transgenic crops in the world

14.00-15.30         Lunch, Poster viewing

15.30-17.30 Session III    Modern Trends in Diagnosis and Therapy of Cancer
Chairpersons: B. Maciejewski, B. Jarząb

B. Utracka-Hutka (Center of Oncology, Gliwice)
Targeted therapy

A. Maciejewski, J. Wierzgoń, C. Szymczyk, B. Mąka (Center of Oncology, Gliwice)
Free flaps in reconstructive surgery in head and neck region

R. Tarnawski (Center of Oncology, Gliwice)
Radiosurgery

B. Białas (Center of Oncology, Gliwice)
SWIFT system for 3D real time brachytherapy planning in prostate cancer

B. Jarząb (Center of Oncology, Gliwice)
Expression profiles in papillary thyroid cancer analysed by DNA microarrays

M. Małecki, P. Janik (Center of Oncology, Warszawa)
Angiogenic gene therapy: a bicistronic strategy

M. Wierzbicka (Institute of Human Genetics, Poznań)
Biological implications of failure in solid tumors treatment

19.00         Social Party

Saturday, November 22nd

9.00-11.00    Session IV DNA repair and their role in carcinogenesis
Session supported by Committee for Human Genetics and Molecular Pathology, PAS
Chairperson: M. Chorąży

R. Oliński (Medical Academy, Bydgoszcz)
The molecular links between oxidative damage to DNA and cancer

M. Kruszewski (Institute of Nuclear Chemistry and Technology, Warszawa)
Labile iron pool, oxidative DNA damage and carcinogenesis

M. Chovanec (Cancer Research Institute, Bratislava)
DNA double-strand break repair and its implication in cancer

R. Goncharova (Institute of Genetics and Cytology, Mińsk)
Some aspects of applying antimutagens as anticarcinogens

J. Rzeszowska (Center of Oncology, Gliwice)
Nucleotide excision repair - new role in oxidative damage repair ?

M. Rusin (Center of Oncology, Gliwice)
DNA repair genes; polymorphisms and risk of cancer

M. Obolenskaya (Institute of Molecular Biology and Genetics, Kijów)
Glutathione transferase activity and genotoxic damage in human placentas from environmentally exposed pregnancies

11.00-11.30         Coffee break

11.30-13.00    Session V   Mathematical Models of in Biology and Medicine
Chairperson: A. Polański

J. Leluk (Warsaw University, Warszawa)
Wrong assumptions and misinterpretations in molecular biology, biochemistry and bioinformatics

A. Masny, A. Płucienniczak (Institute of Biotechnology and Antibiotics, Warszawa)
PCR performed at low denaturation temperatures - PCR melting

J. Polańska (Silesian Technical University, Gliwice)
Using Gaussian mixtures to infer structure in microarray data

T. Magdziarz (University of Silesia, Katowice)
Designing drugs by docking ligands into proteins - chemical problems and technical challenges

M. Pacholczyk (Silesiasian Technical University, Gliwice)
Analysis of differences in protein substitution patterns based on statistical tests

13.00-14.00         Lunch

14.00-16.00 Session VI    Satellite workshop: Cytogenetic Markers in Assessment of Human Exposure to Carcinogenic Substances - Workshop supported by Ministry of Health and Polish Genetic Society
Chairperson: K Szyfter

M. Sąsiadek (Medical University of Wroclaw, Wrocław)
Chromosomal aberrations and cancer risk

M. Dusinská (Institute of Preventive and Clinical Medicine, Bratislava)
Assessment of biomarkers of exposure, effect and individual susceptibility in workers exposed to mineral fibres

F. Marcon, R. Crebelli (Istituto Supriore di Sanita, Rome)
Can current biomarkers be applied in the monitoring of low environmental exposures? Results from an investigation on traffic wardens of Rome city

G. Motykiewicz (Gliwice)
Application of cytogenetic markers in the polluted region of Upper Silesia

E. Skrzydlewska (Medical Academy, Białystok)
Green tea in cancer prevention


16.00         Closing Ceremony

16.15-17.00         Coffee/Discussion