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Gliwice Scientific Meetings 2007 16-17 November Molecular Biology and Bioinformatics in Cancer Diagnostics and Therapy Friday, 16.11.2007 9.00 - Opening Session I Modeling and Synthetic Approaches in Drug Discovery Part A (9.15 -10.30) Chairman: Jarosław Polański Johann Gasteiger (Computer-Chemie-Centre, Erlangen-Nurnberg, Germany) Explorations into Biochemical Pathways Beata Walczak (University of Silesia, Katowice) A start-to-end approach to the analysis of proteomic data Jaroslaw Polanski (University of Silesia, Katowice) The design and discovery of HIV integrase inhibitors Alicja Ratuszna (University of Silesia, Katowice) The new photosensitizers and their application in Photodynamic Therapy Coffee break -10.30 - 10.45 Part B 10.45 - 13.00 Chairman: Wiesław Szeja Timothy Madden (University of Texas MD Anderson Cancer Center, Houston, TX) An approach to drug development in an academic environment Waldemar Priebe (University of Texas, MD Anderson Cancer Center, Houston, TX) Design and development of novel anticancer drugs for treatment of brain tumors Bogdan Lesyng (Warsaw University, Warsaw) Oncogenic JAK/STAT signalling pathways and design of JAK-kinase inhibitors Grzegorz Grynkiewicz (Pharmaceutical Research Institute, Warsaw) Sugars in new drug design - a lesson from natural products with anticancer activity Wiesław Szeja (Silesian University of Technology, Gliwice) Glycoconjugates. Development of a new biologically active compounds Lunch - 13.00 -14.00 Session II (14.00 - 16.45) Ion Channels in Biology and Medicine Chairman: Stanisław Przestalski Mustafa B. A. Djamgoz (Imperial College London, London,UK) Voltage-gated Na channel upregulation and potentation of celloular behaviours in metastatic disease Zbigniew Grzywna (Silesian University of Technology, Gliwice) Wound healing as a diffusional sorption process Steven White (University of California, Irvine, USA) Making Sense of Voltage Sensors Jerzy Mozrzymas (Wrocław Medical University) Pharmacokinetic description of GABAergic current modulation by benzodiazepines in neurons Maria Mycielska (Imperial College London, London,UK) Metabolic pathways in human prostate cancer cells: Regulation by voltage-gated Na channel activity Krzysztof Dołowy (Warsaw University of Life Sciences - SGGW) Ion channels and genetic disorders the cystic fibrosis case Coffee break 16.45 - 17.15 Session III Biotechnologies Part A : (17.15-19.15) Genomics and Proteomics in Medicine Chairman: Piotr Widłak Adam Godzik (Joint Center for Structural Genomics, La Jolla, USA) Metagenomics provides new perspectives on human health Daria Handkiewicz-Junak (MSC Cancer Center and Institute of Oncology, Gliwice) Molecular PET imaging and gene expression profiling of malignant tumors Krzysztof Fujarewicz (Silesian University of Technology, Gliwice) Monte Carlo methods for genomic data analysis Piotr Widłak (MSC Cancer Center and Institute of Oncology, Gliwice) Mass Spectrometry Analyses of the Serum Proteome - an Important Tool of Clinical Proteomics Joanna Polańska (Silesian University of Technology, Gliwice) Application of the Gaussian mixture model to proteomic MALDI-ToF mass spectra Tomasz Bieńkowski (Applera Polska Sp. z.o.o.) "Discovery and Validation of Biomarkers by Mass Spectrometry" Jacek Leluk (University of Zielona Góra) Theoretical background and utility of commonly used sequence multiple alignment tools Get together party 20.00 - Saturday, 17.11.2007 Session III. Biotechnologies Part B: (9.00-10.30) Biomaterials for Regenerative Medicine Chairman: Aleksander L. Sieroń David Hulmes (Institut de Biologie et Chimie des Protéines, CNRS/Université de Lyon, Lyon, France) Controlling the assembly of the cellular microenvironment and applications in tissue regeneration and repair Aleksander Sieroń (Medical University of Silesia, Katowice) Genetic engineering of ECM compounds for regenerative medicine Marek Kowalczuk (PAS, Centre of Polymer and Carbon Materials, Zabrze,) Biopolyesters and their synthetic analogues of controlled structure at the molecular level for regenerative medicine Anna Szydło (Medical University of Silesia, Katowice) Copolymers of synthetic biodegradable scaffold with collagen type I Ksymena Urbanek (Medical University of Silesia, Katowice) Characterization of nonadherent rat bone marrow stem cells (VSEL cells). Coffee break 10.30-10.45 Session IV: New Trends in Cancer Diagnostics and Therapy Part A (10.45 - 13.30) Chairman: Barbara Tudek Thoralf Christoffersen (University of Oslo, Norway) Mechanisms integrating signalling from G protein-coupled receptors and EGF receptors in normal and malignant gastrointestinal cells Dagny Sandness (University of Oslo, Norway) Role of different prostanoid receptors in the growth-stimulatory effects of prostaglandins Barbara Tudek (Institute of Biochemistry and Biophysics, PAS, Warsaw) DNA repair in the pathology of lung and colon cancer Carmel Mothersill (McMaster University, Hamilton, Canada) Harnessing low dose radiation responses for radiation protection Colin Seymour (McMaster University, Hamilton, Canada) Natural products as radiation response modifiers Raisa Smolyakova (N.N. Alexandrov Research Institute of Oncology and Medical Radiology, Minsk) Prognostic molecular biologic markers in breast cancer Lunch 13.30-14.30 Poster Session 14.30 - 15.30 Session IV: New Trends in Cancer Diagnostics and Therapy Part B (15.30 - 17.30) Chairman: Marek Los Walter Mier (Universitätsklinikum Heidelberg, Heidelberg) The potential of endoradiotherapy for the development of highly specific cytostatics Dariusz Iżycki (University of Medical Sciences at GreatPoland Cancer Center, Poznan) Genetic antimelanoma vaccines - promises and obstacles Marek Los (Manitoba Institute of Cell Biology, Winnipeg, Canada) Targeted cancer therapies using derivates of natural products - Brevinin-2R and Apoptin as examples Maciej Giefing (Institute of Human Genetics, PAS, Poznan) Array-GCH based identification of oncogenes and tumor suppressor genes involved in laryngeal cancer Maria Obolenskaya (Institute of Molecular Biology and Genetics, NAS, Kiev) Novel approach in the study of IFN alpha activity Krzysztof Puszyński (Silesian University of Technology, Gliwice) Deterministic model of p53|Mdm2 signaling pathway Closing Ceremony 17.30 |
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