XXVII Gliwice Scientific Meetings, 2023
70th anniversary of DNA helix: Nucleic acid structure meets function
Thursday, 16th November 2023
9.00 Opening of the conference and the Professor Chorąży Lecture 2023
Victor Ambros (University of Massachusetts, Worcester):
Genetic regulatory networks involving noncoding RNA
10.00 Session: Helical structures, molecular crowding, and nuclear processes tribute to Prof. Ronald Hancock
Thomas Cremer (Ludwig-Maximilians-University, Munich): Major differences of chromatin compaction and accessibility between active and inactive nuclear compartments
Marion Cremer (Ludwig-Maximilians-University, Munich): Topography of replication domains in nuclear landscapes studied with super-resolution microscopy: local details and global context
Tobias Aurelius Knoch (Erasmus University Medical Center, Rotterdam): On the essence of existence: how the finalization of the 3D genome organization leads to a novel generalized/unified evolution theory
Jekaterina Erenpreisa (Latvian Biomedical Research and Study Centre, Riga, Latvia): Thermodynamics and positional information of heterochromatin, adaptive interaction with DNA code
Aleksandra Pękowska (Nencki Institute of Experimental Biology, Warszawa): Mechanisms shaping the consolidation of chromatin architecture upon loss of pluripotency
Yegor Vassetzky (CNRS, Gustave Roussy Institute, Villejuif): Factors that affect the formation of chromosomal translocations
Jerzy Dobrucki (Jagiellonian University, Kraków): title pending
Tomasz Sarnowski (Institute of Biochemistry and Biophysics, Warszawa): Impairment of SWI/SNF chromatin remodeling complex in cancer development and progression
Lunch and Poster Session
16.30 Session: Role of the helix in RNA
Gunter Meister (University of Regensburg, Regensburg): Mechanisms of m6A- and miRNA-guided gene regulation and their links to cancer progression
Jan Barciszewski (Institute of Bioorganic Chemistry, Poznan): title pending
Martin Simard (Laval University, Quebec): Uncovering the regulation of the microRNA-mediated gene regulatory pathway in animals
Antonio Monari (Unoiversité Paris Cité, Paris): How is DNA and RNA 3D structures shaping viral reproduction and immune system response? The answer comes from molecular modeling and simulation
Alice Ghidini (Sixfold Bioscience, London): Embedding natural RNA-protein binding mechanism in RNA-based delivery scaffolds
20.00 - Social event and conference dinner
Friday, 17th November 2023
9.00 Session: Artificial Intelligence and Modeling in Molecular Biology and Medicine
Tibor Antal (Edinburgh University School of Mathematics): Models of cancer initiation, progression, and metastasis formation
Marek Kimmel (Rice University, Houston): Site frequency spectra of tumor genomes: estimating past dynamics of growth and mutation
Tone F. Bathen (NTNU, Trondheim): Radiomics-based machine learning for prediction of clinically significant prostate cancer using mpMRI
Joanna Polańska (Silesian University of Technology, Gliwice): title pending
Anna Karpukhina (CNRS, Gustave Roussy Institute, Villejuif): Super-enhancers in Mantle Cell Lymphoma
11.20 Lunch
12.00 Session: Cancer Proteomics and Metabolomics
Guro F. Giskeødegård (NTNU, Trondheim): Changes in circulating metabolites and lipoprotein subfractions after breast cancer treatment
Malcolm R. Clench (Sheffield Hallam University, Sheffield): Mass Spectrometry Imaging of metabolic processes in 3D tissue models
Laura Cole (Sheffield Hallam University, Sheffield): Multimodal Mass Spectrometry Imaging of ocular disease
Piotr Młynarz (Wrocław University of Science and Technology, Wrocław): Kidney cancer recognition in men and women population
Sachin Kote (University of Gdańsk, Gdańsk): Serum Peptidomics: novel approaches to cancer diagnostics, prognosis, and monitoring
Anna Wojakowska (Institute of Bioorganic Chemistry, Poznań): Molecular predictors of colorectal cancer metastasis
Monika Drobna-Śledzińska (Institute of Human Genetics Polish Academy of Sciences, Poznań): Proteomics unravels novel miR-363-3p targets implicated in JAK-STAT pathway upregulation in T-cell acute lymphoblastic leukemia
14.50 Poster Session – Presentations of Awarded Posters
15.30 Closing remarks, coffee and free discussions