XXVI Gliwice Scientific Meetings, 2022
Scientific Program
Friday, 18th November 2022
9.00 – 9.15
Opening of the conference and announcement of prof. Mieczysław Chorąży Fellowship laureate
9.15 – 9.50 Professor Mieczysław Chorąży Lecure 2022:
Philip Maini (Wolfson Centre for Mathematical Biology, Oxford): Can mathematical modelling help us understand cancer growth and progression?
9.50 – 10.00 Coffee Break
10.00 – 13.00 Session “New and experimental cancer therapies and approaches”
Chairpersons – Tomasz Cichoń and Ryszard Smolarczyk
Tatsuya Morisaki (Colorado State University, Fort Collins): Technology developments to visualize and quantify translation at single molecule resolution in living cells.
Jesus Prieto (University of Navarra, Pamplona): An AAV-based platform for cancer immunotherapy.
Sebastian Giebel (NRIO, Gliwice): Chimeric antigen receptor (CAR) T- cells in oncology. Current status and future perspectives.
Urszula Foryś (Warsaw University, Warszawa): Can a CAR-T cell treatment be efficient against solid tumors? A mathematical insight.
11.30 – 11.45 Coffee Break
Ekaterina Pylaeva (University Hospital, Essen): Therapeutic modulation of neutrophil tumorigenic activity in head-and-neck tumor.
Aleksander Sochanik and Joanna Jazowiecka-Rakus (NRIO, Gliwice): A novel viral oncolytic and chemotherapeutic combination approach to glioma therapy.
Ryszard Smolarczyk (NRIO, Gliwice): The tumor microenvironment polarization as a goal of cancer immunotherapy.
Dorota Ścieglińska (NRIO, Gliwice): Reconstructed human epidermis for in vitro studies on the HSPA2 gene function.
Paweł Kania (NanoTemper Technologies): Employing Spectral Shift Technology and Microscale Thermophoresis in the modern drug discovery. Monolith.
13.00 – 13.15 Coffee Break
13.15 – 14.45 Session “Biology of Extracellular Vesicles” (part 1)
Chairpersons – Monika Pietrowska and Piotr Widłak
Janusz Rak (McGill University, Montreal): Oncogenes, extracellular vesicles and cancer-associated vascular pathology.
Fabrice Lucien-Matteoni (Mayo Clinic, Rochester): Tumor-derived extracellular vesicles in antitumor immunity and response to radiotherapy.
Jan Kranich (Ludwig-Maximilians-University, Munich): Extracellular vesicles from antigen-presenting cells boost TCR-signaling and effector gene expression in CD8+ T cells during viral infections.
14.45 – 16.15 Lunch and Poster Session
16.15 – 18.00 Session “Biology of Extracellular Vesicles” (part 2)
Jadwiga Jabłońska (University Hospital, Essen): Modulation of tumorigenic activity of neutrophils via tumor-derived EVs.
Piotr Widłak (Medical University of Gdańsk, Gdańsk): Radiation-induced bystander effect mediated by exosomes involves the replication stress in recipient cells.
Anna Wojakowska (Institute of Bioorganic Chemistry, Poznań): Metabolomic and proteomic profiling of serum exosomes from cancer patients treated by radiotherapy.
Aneta Żebrowska (NRIO, Gliwice): Proteomic and metabolomic profiles of T cell-derived exosomes isolated from human plasma.
Daniel Fochtman: In vitro and in vivo neutrophil models overview – an examination of advantages and disadvantages for neutrophil-derived small extracellular vesicles release.
19.00 – Conference dinner
Saturday, 19th November 2022
9.00 – 11.30 Session “Oncology Meets Physics, Mathematics and Numerical Methods” (part 1)
Chairpersons – Zbigniew Grzywna and Krzysztof Fujarewicz
Khanh Ngoc Dinh (Rice University, Houston): Modeling and simulation of cancer evolution in single cells.
Philip Maini (Oxford University, Oxford): Mathematical challenges arising in cancer modeling.
Bartłomiej Wacław (University of Edinburgh, Edinburgh): Darwinian evolution in spatial models of cancer.
Ryszard Rudnicki (Institute of Mathematics, Warszawa): Some aspects of mathematical modeling of cell cycle.
Krzysztof Fujarewicz (Silesian University of Technology, Gliwice): Individualized and personalized models in biology and medicine.
Krzysztof Puszyński (Silesian University of Technology, Gliwice): Mathematical modelling and analysis to search for molecular targets for therapy.
11.30 – 11.45 Coffee Break
11.45 – 12.30 Session “Oncology Meets Physics, Mathematics and Numerical Methods” (part 2)
Roman Jaksik (Silesian University of Technology, Gliwice): Whole genome sequencing - beyond driver mutation discovery.
Paulina Trybek (Silesian University, Katowice) and Agata Wawrzkiewicz-Jałowiecka (Silesian University of Technology, Gliwice): On the use of nonlinear methods of patch-clamp data analysis to unravel the unical features of the BK channel gating in human glioblastoma cells.
12.30 – 14.10 Session “Modifications of Nucleic Acids and Cancer”
Chairpersons – Marek Foksiński
Edyta Reszka (Nofer Institute of Occupational Medicine, Lodz): Epigenetics of a molecular clock in cancer.
Tomasz K. Wojdacz (Pomeranian Medical University, Szczecin): Increasing significance of methylation biomarkers in clinical cancer management.
Marta Starczak (Collegium Medicum, Bydgoszcz): N6-methyladenine metabolism – potential relationships with leukemia development.
Joanna Bogusiewicz (Collegium Medicum, Bydgoszcz): New diagnostic opportunities in oncology based on microextraction methods.
Maciej Gawroński (Collegium Medicum, Bydgoszcz): Vitamin C as a key regulator of the active DNA demethylation process.
14.10 – 14.40 Poster Session – Presentations of Awarded Posters
14.40 – Closing Remarks
14.45 – Lunch