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18-19 Nov 2022

 

Gliwice

 

ASCR

 

NIO

 

PolSL

 

PAN

 

XXVI Gliwice Scientific Meetings, 2022

Scientific Program

 

Conference Materials

 

Friday, 18th November 2022

9.00 – 9.15          

Opening of the conference and announcement of prof. Mieczysław Chorąży Fellowship laureate

9.15 – 9.50           Professor Mieczysław Chorąży Lecure 2022:

Philip Maini (Wolfson Centre for Mathematical Biology, Oxford): Can mathematical modelling help us understand cancer growth and progression?

9.50 – 10.00         Coffee Break

10.00 – 13.00      Session “New and experimental cancer therapies and approaches

Chairpersons – Tomasz Cichoń and Ryszard Smolarczyk

Tatsuya Morisaki (Colorado State University, Fort Collins): Technology developments to visualize and quantify translation at single molecule resolution in living cells.

Jesus Prieto (University of Navarra, Pamplona): An AAV-based platform for cancer immunotherapy.

Sebastian Giebel (NRIO, Gliwice): Chimeric antigen receptor (CAR) T- cells in oncology. Current status and future perspectives.

Urszula Foryś (Warsaw University, Warszawa): Can a CAR-T cell treatment be efficient against solid tumors? A mathematical insight.

11.30 – 11.45      Coffee Break

Ekaterina Pylaeva (University Hospital, Essen): Therapeutic modulation of neutrophil tumorigenic activity in head-and-neck tumor.

Aleksander Sochanik and Joanna Jazowiecka-Rakus (NRIO, Gliwice): A novel viral oncolytic and chemotherapeutic combination approach to glioma therapy.

Ryszard Smolarczyk (NRIO, Gliwice): The tumor microenvironment polarization as a goal of cancer immunotherapy.

Dorota Ścieglińska (NRIO, Gliwice): Reconstructed human epidermis for in vitro studies on the HSPA2 gene function.

Paweł Kania (NanoTemper Technologies): Employing Spectral Shift Technology and Microscale Thermophoresis in the modern drug discovery. Monolith.

13.00 – 13.15      Coffee Break

13.15 – 14.45      Session “Biology of Extracellular Vesicles” (part 1)

Chairpersons – Monika Pietrowska and Piotr Widłak

Janusz Rak (McGill University, Montreal): Oncogenes, extracellular vesicles and cancer-associated vascular pathology.

Fabrice Lucien-Matteoni  (Mayo Clinic, Rochester): Tumor-derived extracellular vesicles in antitumor immunity and response to radiotherapy.

Jan Kranich (Ludwig-Maximilians-University, Munich): Extracellular vesicles from antigen-presenting cells boost TCR-signaling and effector gene expression in CD8+ T cells during viral infections.

14.45 – 16.15      Lunch and Poster Session

16.15 – 18.00      Session “Biology of Extracellular Vesicles” (part 2)

Jadwiga Jabłońska (University Hospital, Essen): Modulation of tumorigenic activity of neutrophils via tumor-derived EVs.

Piotr Widłak (Medical University of Gdańsk, Gdańsk): Radiation-induced bystander effect mediated by exosomes involves the replication stress in recipient cells.

Anna Wojakowska (Institute of Bioorganic Chemistry, Poznań): Metabolomic and proteomic profiling of serum exosomes from cancer patients treated by radiotherapy.

Aneta Żebrowska (NRIO, Gliwice): Proteomic and metabolomic profiles of T cell-derived exosomes isolated from human plasma.

Daniel Fochtman: In vitro and in vivo neutrophil models overview – an examination of advantages and disadvantages for neutrophil-derived small extracellular vesicles release.

19.00 –                  Conference dinner

Saturday, 19th November 2022

9.00 – 11.30        Session “Oncology Meets Physics, Mathematics and Numerical Methods” (part 1)

Chairpersons – Zbigniew Grzywna and Krzysztof Fujarewicz

Khanh Ngoc Dinh (Rice University, Houston): Modeling and simulation of cancer evolution in single cells.

Philip Maini (Oxford University, Oxford): Mathematical challenges arising in cancer modeling.

Bartłomiej Wacław (University of Edinburgh, Edinburgh): Darwinian evolution in spatial models of cancer.

Ryszard Rudnicki (Institute of Mathematics, Warszawa): Some aspects of mathematical modeling of cell cycle.

Krzysztof Fujarewicz (Silesian University of Technology, Gliwice): Individualized and personalized models in biology and medicine.

Krzysztof Puszyński (Silesian University of Technology, Gliwice): Mathematical modelling and analysis to search for molecular targets for therapy.

11.30 – 11.45      Coffee Break

11.45 – 12.30        Session “Oncology Meets Physics, Mathematics and Numerical Methods” (part 2)

Roman Jaksik (Silesian University of Technology, Gliwice): Whole genome sequencing - beyond driver mutation discovery.

Paulina Trybek (Silesian University, Katowice) and Agata Wawrzkiewicz-Jałowiecka (Silesian University of Technology, Gliwice): On the use of nonlinear methods of patch-clamp data analysis to unravel the unical features of the BK channel gating in human glioblastoma cells.

12.30 – 14.10      Session “Modifications of Nucleic Acids and Cancer” 

Chairpersons – Marek Foksiński

Edyta Reszka (Nofer Institute of Occupational Medicine, Lodz): Epigenetics of a molecular clock in cancer.

Tomasz K. Wojdacz (Pomeranian Medical University, Szczecin): Increasing significance of methylation biomarkers in clinical cancer management.

Marta Starczak (Collegium Medicum, Bydgoszcz): N6-methyladenine metabolism – potential relationships with leukemia development.

Joanna Bogusiewicz (Collegium Medicum, Bydgoszcz): New diagnostic opportunities in oncology based on microextraction methods.

Maciej Gawroński (Collegium Medicum, Bydgoszcz): Vitamin C as a key regulator of the active DNA demethylation process.

14.10 – 14.40      Poster Session – Presentations of Awarded Posters

14.40 –                 Closing Remarks

14.45 –                  Lunch